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Publications

Stefaan Verbruggen Stefaan Verbruggen

Deep learning models to map osteocyte networks

A machine learning study in which neural networks were trained to map and characterise the osteocyte networks in young and aged bone, published in the journal PLoS Computational Biology in 2026 and available here.

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Stefaan Verbruggen Stefaan Verbruggen

Multi-omics qualification bone cancer organ-chips

A qualification study using transcriptomics and proteomics to validate a mouse organ-chip model of osteolytic metastases against data from the mouse model, published in the journal Acta Biomaterialia in 2026 and available here.

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Stefaan Verbruggen Stefaan Verbruggen

Air Pollution and Osteoporosis

A review of the emerging link between airborne pollutants and bone degeneration, published in the journal Current Osteoporosis Reports in 2024 and available here.

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Stefaan Verbruggen Stefaan Verbruggen

3D Models of the Multiple Myeloma Microenvironment

A review of advanced models that are being developed to replicate Extra Medullary Disease, whereby myeloma cells escape the bone marrow microenvironment to metastasise to other tissues, published in the journal Cancers in 2024 and available here.

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Stefaan Verbruggen Stefaan Verbruggen

Role of the osteocyte in bone metastasis

An invited review of the emerging role played by osteocytes in mediating development of metastatic nice he in breast and prostate cancer metastatic colonies, published in the Journal of Bone Oncology in 2024 and available here.

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Stefaan Verbruggen Stefaan Verbruggen

Osteocytes and Primary Cilia

A review of the primary cilium and its mediating role in osteocyte mechanotransduction, published in Current Osteoporosis Reports in 2023 and available here.

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Stefaan Verbruggen Stefaan Verbruggen

Disrupted osteocyte mechano-biology in aging

A study combining transcriptomics (RNAseq) and computational modelling (CFD) to investigated the role played by aging and TGF-β in osteocyte mechanosensing, published in the Proceedings of the National Academy of Sciences (PNAS) in 2021.

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Stefaan Verbruggen Stefaan Verbruggen

Ontogeny of the human pelvis

A review of the development of the human pelvis in individuals, published in the Anatomical Record in 2017.

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